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Nubello Restylane

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Nubello Introduce

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Advance Antiaging Treatment

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Restylane Sweden



On the 28th of May in Germany, I will reveal the natural-looking result of Restylane and Restylane Skinboosters in real life.
The spectacular event and the reactions will be shared first on this website.
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  • About Nubello-Restylane
  • Is Nubello-Restylane safe?
  • Is Nubello-Restylane Right for me?
  • Products
  • Treatment
  • FAQ
  • Results

The science behind Nubello-Restylane.

The Nubello-Restylane range of products are made in Sweden, a country known for it’s beauty. All products* are based on hyaluronic acid***, a natural substance found in your own skin. Our patented NASHA™ technology for the production of stabilised hyaluronic acid is the secret behind the Nubello-Restylane range.
Hyaluronic Acid
Hyaluronic acid is one of nature’s most versatile and fascinating substances. It is found throughout the human body as well as in most other living organisms. It has many functions, including giving our skin elasticity and providing volume, resulting in a youthful appearance.


Why is Nubello-Restylane unique?

The patented NASHA technology is unique to Nubello-Restylane Skinbooster and filler products. This means that unlike other hyaluronic acid aesthetic treatments, the hyaluronic acid found in Nubello-Restylane differs only slightly from your skin’s own natural hyaluronic acid (~1%). The result is a range of natural and safe aesthetic treatments that are long lasting but not permanent, allowing you to change your look over time.

With so many different aesthetic treatments available today, what makes Nubello-Restylane so unique and trusted by millions all over the world?

Since its launch in 1996 over 20 million treatments* have been performed worldwide. With two decades of heritage, the company behind Nubello-Restylane, Galderma is devoted to continued research and development to ensure both you the patient and aesthetic practitioners are provided with market leading products.
Nubello-Restylane was the first hyaluronic acid dermal filler aesthetic treatment to be approved by the FDA (United States Food and Drugs Administration) and is regarded highly in proven quality, efficacy and safety – with over 50 clinical studies to date.


The Nubello-Restylane range of aesthetic treatments are designed to address both the cause and effect of the problem of ageing skin. The various products in the Nubello-Restylane filler and Skinbooster range are designed specifically to work with your skin to give you a natural result you’ll love.

Can anyone have a Nubello-Restylane treatment?
Most people can benefit from a Nubello-Restylane treatment however in order to meet your individual treatment needs, discuss your desires with a qualified Nubello-Restylane Practitioner.

Nubello-Restylane should not be used in or near areas where there is or has been skin disease, inflammation or skin related problems. No skin test is required as Nubello-Restylane does not contain any animal-derived ingredients.



With over 20 million treatments* performed worldwide since launch, Nubello-Restylane has the product to suit your anti-ageing treatment needs. As experts in the skin, Nubello-Restylane have also developed a skincare range to complement your aesthetic treatment or to use as part of your daily skincare regime.

Nubello-Restylane Fillers

Smooth away wrinkles and lines or add volume to your facial features.

As we age, wrinkles, lines, folds – whatever you want to call them appear on our faces. This is caused by a number of factors, from the environment to genetics. Nubello-Restylane fillers are designed to help smooth away wrinkles and lines, by adding volume under your skin where it is needed most. Nubello-Restylane fillers can also be used to restore volume to sunken cheeks and give you that kissable smile you’ll love.

Each Nubello-Restylane filler product is specifically formulated to boost volume in a targeted layer of skin to give maximum affect. Administered by your qualified Nubello-Restylane practitioner, the Nubello-Restylane fillers range are used to provide non surgical cosmetic enhancements to help you reach your full potential.

All of the products are available with 0.3% lidocaine anaesthetic providing you with the most comfortable treatment possible.



Nubello-Restylane - The first hyaluronic acid dermal filler approved by the FDA.
Nubello-Restylane is specifically designed to reduce moderate facial wrinkles and folds, such as nose to mouth lines.
It can also be used to treat smile lines and marionette lines at the corners of the mouth.


Moderate facial wrinkles – e.g. frown lines and soft nose to mouth lines.
Nubello-Restylane is also available with 0.3% lidocaine (a type of anaesthetic) for increased
comfort during treatment.



Nubello-Restylane Perlane- Smooth deeper wrinkles and folds such as deep nose to mouth lines or subtly restore lost volume to your facial features.
A Nubello-Restylane Perlane treatment provides shaping for facial contours such as minor to moderate contouring of the cheek or eyebrow area, and accentuating the existing features, as well as smoothing out deeper wrinkles and folds.


Deep wrinkles and folds, minor to moderate facial contouring, eg, cheek enhancement.
Nubello-Restylane Perlane is also available with 0.3% lidocaine (a type of anaesthetic) for increased comfort during treatment.



Nubello-Restylane SubQ - Enhance your facial features by replacing or adding volume to your cheeks or chin.
Nubello-Restylane SubQ is injected deeper than other Nubello-Restylane products to add or restore lost volume and support to the overall skin structure, providing facial fullness and restoring symmetry. Youthful cheeks can be restored and facial features better defined.


Facial contouring (chin and cheek shaping)
Nubello-Restylane SubQ is also available with 0.3% lidocaine (a type of anaesthetic) for increased comfort during treatment.

Nubello-Restylane Skinboosters


Whilst the Nubello-Restylane filler range is designed specifically to replace volume where it has been lost through ageing, a course of Nubello-Restylane Skinboosters hydrate from within to treat and improve the overall condition of your skin.
Nubello-Restylane Skinboosters are designed to restore hydration in the skin, resulting in long lasting improvements in skin quality and condition. A series of tiny injections, made more comfortable with an anaesthetic called lidocaine included in the range, are given resulting in improved skin tone and skin elasticity. Skinbooster treatments with the Nubello-Restylane range hydrate the skin and are perfect for treating the face, hands, neck, décolletage and lips where over exposure to the sun can cause premature ageing.



Nubello-Restylane Vital Skinboosters, are part of our range of specifically designed treatments to give your skin deep dermal hydration from within.
The natural hydrating properties of Nubello-Restylane Vital make it the obvious choice for skin areas that take on a dehydrated appearance with over exposure to the sun. These areas typically include;

  • The face
  • The décolletage
  • The backs of hands

Nubello-Restylane Vital is a slightly stronger product than Nubello-Restylane Vital Light with a greater concentration of natural hyaluronic acid to provide greater hydration to the areas that need it most.


Nubello-Restylane Vital Light is part of our Skinbooster range providing hydration to more delicate, thinner areas of the skin.
Nubello-Restylane Vital Light like other products in the Nubello-Restylane Skinboosters range is designed to restore the skins natural hydration. Nubello-Restylane Vital Light is specifically designed to treat less photo damaged (sun damaged skin) and sensitive skin areas such as;

  • Crows feet around the eyes
  • Peri-oral area around the top lip
  • The neck
  • The backs of hands where skin is thinner
  • The décolletage where skin is thinner

Wrinkle Treatment

Sometimes the best aesthetic treatment is a simple injection procedure to smooth out wrinkles and folds. In certain cases wrinkles don’t add character to your face but make you feel older than you feel on the inside. With Nubello-Restylane fillers and Skinboosters, your looks can be quickly enhanced with long-lasting results.
Whatever your needs are, from smoothing nose to mouth lines or improving the appearance of frown lines – there’s a Nubello-Restylane solution that gives the best possible results.


As we get older, facial muscles begin to slacken and your skin becomes less elastic. This creates fine lines, moderate lines or deeper folds in the skin that we call wrinkles. They are found where your facial muscles move and you can get frown lines, forehead lines and squint lines at the corners of your eyes, known as crow’s feet. Deeper folds may appear between your nose and mouth known as nasolabial folds. These wrinkles are a result of lost facial volume that occurs as we age.


Wrinkles are part of the natural ageing process. Genetics play an important part, however, environmental factors, such as ultraviolet (UV) radiation from the sun and smoking, can dry your skin and make wrinkles appear at a younger age. An unhealthy diet may also cause wrinkles to appear sooner.

Wrinkles usually appear on areas of your skin that are most exposed to the sun, such as your face, neck, backs of your hands and upper arms. This is because UV radiation from the sun damages the DNA in your skin cells, which causes your skin to age. Whilst some sunlight is important because your skin uses it to produce vitamin D, too much sun is harmful and people who spend a lot of time in the sun, particularly without protecting their skin with sunscreen, may develop fine lines and wrinkles at an earlier age.

Cigarette smoke affects your skin in several ways. It dries your skin out and it constricts your blood vessels. This reduces the supply of oxygen and vital nutrients to your skin. Research suggests that smoking may also cause an increase in the production of an enzyme that breaks down collagen – the part of your skin that keeps it looking firm. As a result, people who smoke are more likely to have facial wrinkles at a younger age. Puckering up your lips when you smoke also causes lines to form around your mouth (known as smoker’s lines) and eyes.


Hyaluronic acid (HA) is found in the skin and is a naturally occuring substance that helps to keep the skin looking young, wrinkle free and full. As we age our body will naturally produce less HA which is what causes the skin to look older and when you will see depressions in the skin, especially the face. Nubello-Restylane products are designed to help replace some of the lost HA to smooth wrinkles and hollows.


Fortunately, help is at hand with Nubello-Restylane filler andSkinboosters treatments. By softly replacing lost hyaluronic acid in the skin, Nubello-Restylane fillers can help smooth away wrinkles, whilst Nubello-Restylane Skinboosters help revitalise and hydrate the skin to counter the effects of fine lines.
Treatments for facial lines and wrinkles
Treatments for wrinkles around the eyes
Over 20 million* Nubello-Restylane filler and Skinboosters treatments have been carried out since launch, contact your local qualified Nubello-Restylane Practitioner today and discover what Nubello-Restylane treatmens can do for you.

What is Nubello-Restylane?

Nubello-Restylane is a range of products for facial aesthetic treatments made in Sweden. They are designed to effectively reduce the appearance of unwanted wrinkles, contour and create volume in facial features such as the cheeks, chin and lips, and to revitalise the skin. Nubello-Restylane is a gel based on stabilised hyaluronic acid. Hyaluronic acid (HA) is a substance that naturally exists in your body. The gel is injected into the skin through a needle or cannula by a trained Nubello-Restylane practitioner (in the UK a Nubello-Restylane practitioner is a medical professional such as Plastic Surgeon, Cosmetic Doctor, Dermatologist, Costmetic Dentist, or Aesthetic Nurse).
Since 2010, the Nubello-Restylane range has been extended to include a skincare range which can be used in conjunction with Nubello-Restylane treatments, or as a skincare regime in it’s own right.

What is hyaluronic acid?

Hyaluronic acid is a sugar molecule that exists naturally in almost all living organisms. It binds water and can act as a lubricant and shock absorber in movable parts of the body such as joints. It is also important for the transport of nutrients, regulating water balance and giving volume and structure to our skin.

What are the benefits of Nubello-Restylane?

A treatment with Nubello-Restylane provides an easy way to enhance your appearance. The result of a single treatment can be seen instantly, and lasts around one year*,**. With Nubello-Restylane you will achieve a natural looking result that does not affect facial expression.

Nubello-Restylane is the most scientifically documented HA based dermal filler in the world with comprehensive studies that support its safety and efficacy. Nubello-Restylane has been used in over 20 million treatments*** worldwide since 1996.
Nubello-Restylane filler treatments and lip enhancement results can be seen instantly. Nubello-Restylane Skinbooster treatments require an initial course of treaments for the best aesthetic outcome, consult your Nubello-Restylane practitioner to discuss your personal treatment needs. Duration can vary and is dependant upon your body’s own metabolism, genetics, lifestyle as well as area treated.

* Narins RS et al. Dermatol Surg 2008; 34 Suppl 1: S2–8.
** Narins RS et al. Dermatol Surg 2011; 37(5): 644–650
*** Galderma data on file

Why should I choose Nubello-Restylane?

Nubello-Restylane resembles the body’s own hyaluronic acid, which reduces the risk of allergic reaction. Nubello-Restylane is the most tried and tested HA dermal filler available today. Nubello-Restylane has long-lasting results, but is not permanent – allowing you to change your look subtly over time. It is clinically proven with extensive clinical documentation and has been the most widely used. Over 20 million treatments* worldwide have been performed since 1996

What areas can be treated?

Nubello-Restylane products can be used to smooth away facial lines and wrinkles, create fuller lips and shape facial contours, such as cheeks and chin, and revitalise the skin.
The most common areas treated are:

1. Nose to mouth lines (the nasolabial folds)
2. Between the eyebrows (the glabella lines)
3. Lip enhancement (adding volume, shape and hydrating lips)
4. Cheeks and chin (shaping and contouring)
5. Back of the hands, décolletage, face, neck (skin revitalisation)

Discuss your treatment needs at a consultation with your trained Nubello-Restylane practitioner. For more information on which areas can be treated with Nubello-Restylane visit our treatments area to discover more.

How does Nubello-Restylane work?

By boosting the skin’s supply of hyaluronic acid, Nubello-Restylane revitalises and adds volume to the skin, instantly diminishing the appearance of lines and wrinkles, and giving a natural softer look. Nubello-Restylane is a soft injectable gel consisting of stabilised (minimally modified), non-animal hyaluronic acid. The gel is tissue-friendly and closely resembles the hyaluronic acid that exists naturally in the body. It is long-lasting but not permanent.

The Nubello-Restylane range of dermal fillers are specifically designed to add volume to facial features, improving facial contours. There are a number of different Nubello-Restylane fillers, each designed to work at different levels of the skin for the optimum treatment outcome.


Start by making an appointment with a qualified practitioner. During consultation be prepared to discuss your treatment expectations. After discussion of what you wish to achieve and assessment of your treatment needs, your practitioner will recommend which Nubello-Restylane treatment is most suitable for you.

After the consultation, and if you are happy to proceed, your practitioner will help you complete a medical history form and you will need to sign a consent form before treatment can progress.

Treatment is simple and quick and normally takes around 15-20 minutes. Nubello-Restylane fillers are injected into the skin in small amounts using a very fine needle or cannula. The gel provides natural volume to smooth away the appearance of lines and wrinkles, enhance facial shape, or create fuller lips. Nubello-Restylane Skinbooster products improve the elasticity and texture of skin, maintaining and restoring the skins hydrobalance by injecting a number of tiny ‘droplets’ of hyaluronic acid gel into the skin.

The treatment is quick, typically taking about 15-30 minutes. Treatment with Nubello-Restylane does not affect facial expression and the benefits can normally be seen instantly – see our Nubello-Restylane results page.

The treatment benefits can be seen instantly. You can expect slight redness, swelling, pain, tenderness, itching and/or bruising following a treatment. This is the same as you might expect with any type of injection. However, this is temporary and generally disappears after a few days. Nubello-Restylane products are biodegradable, which means they will naturally disappear in the body. To ensure an optimal and long lasting result, a top-up treatment is recommended 6-12 months after your initial Nubello-Restylane treatment. Discuss with your practitioner when a follow-up appointment may be appropriate.

What should I bear in mind when considering a treatment?

First of all you should always contact a qualified practitioner (visit the Nubello-Restylane Practitioner Finder to find clinics offering Nubello-Restylane in your area) to be assured that the treatment will be performed correctly. Nubello-Restylane treatments should only ever be administered by a trained medical healthcare professional (you can check they are registered with their appropriate professional organisation). In the UK & Republic of Ireland this includes;

Plastic Surgeon
Cosmetic Doctor
Cosmetic Dentist
Aesthetic Nurse Practitioner

For your safety, be prepared to discuss your medical history during your pre-treatment consultation to ensure Nubello-Restylane is right for you. Your treatment should be undertaken in a medical environment, ask to see the treatment room and make sure it affords you privacy and is spotlessly clean.

You may want to request to see your chosen practitioners training certificate and insurance certificate to ensure they are appropriately trained and insured for the treatment they are providing.

How long does a Nubello-Restylane treatment last?

One of the great advantages of Nubello-Restylane is that the effects are long lasting but not permanent. Duration depends on many factors, such as the individual’s skin type, skin condition lifestyle and age, and also the area treated.
After the initial treatment, follow-up sessions are normally recommended around every 6 to 12 months depending on the individual and the area treated.
It is recommended for a treatment with Nubello-Restylane Skinboosters that an initial course of approximately 3 treatments each spaced 4 weeks apart is given for the best aesthetic outcome, with a follow up session required 6 to 12 months afterwards.
A lip enhancement treatment with Nubello-Restylane Lip Volume lasts approximately 6 months.
Consult your practitioner for further information based on your individual needs.

Can everybody use Nubello-Restylane?

Most people can benefit from Nubello-Restylane treatment. If you wish to;

1. Reduce lines and wrinkles
2. Create more defined or fuller lips,
3. Define the contours and facial features of your face, such as chin or cheek,
4. Boost your skin’s vitality, for a healthier more hydrated skin tone (e.g.
face, hands, neck or décolletage)

Nubello-Restylane should not be used in or near areas where there is or has been skin disease, inflammation or skin related problems. Nubello-Restylane has not been tested in pregnant or breast-feeding women, individuals with medical conditions that lower the body’s immune response or individuals undergoing therapy that is immunosuppressive may be more prone to infection by a skin injection procedure.
During your pre-treatment consultation, you should thoroughly discuss your medical history with your Nubello-Restylane practitioner.

Does Nubello-Restylane treatment need pain relief?

All products in the Nubello-Restylane Filler and Skinbooster range are now available with 0.3% local anaesthetic lidocaine included for a more comfortable treatment experience.
Generally, further pain relief is not necessary when injecting into the skin to correct lines and wrinkles. Some people may experience the treatment as a mild discomfort. A local anaesthetic topical cream can be applied to the area prior to treatment for a more comfortable experience, by your Nubello-Restylane practitioner.
The lips are a highly sensitive part of the body and, therefore, additional anaesthesia may be required before lip enhancement. This is achieved most effectively by using a dental block or local anaesthetic.
Your Nubello-Restylane practitioner will be able to advise on suitable anaesthesia for your treatment.

Are there any risks with Nubello-Restylane?

More than 20 million treatments* have been performed since the launch of Nubello-Restylane in 1996. Product related reactions are rare. There are some injection related reactions which may occur after any injection; they typically resolve spontaneously a few days after injection to the skin, within a week after injection into the lips and within two weeks after injection with Nubello-Restylane SubQ. These reactions include redness, swelling, pain, itching, bruising or tenderness at the injection site.

After lip enhancement, lips may swell for up to a week, but this typically reduces after two to three days.

You should discuss side effects and post treatment reactions with your aesthetics practitioner. In case of more pronounced reactions or if they last longer than a week contact your practitioner.

Does Nubello-Restylane treatment need pain relief?

All products in the Nubello-Restylane Filler and Skinbooster range are now available with 0.3% local anaesthetic lidocaine included for a more comfortable treatment experience.
Generally, further pain relief is not necessary when injecting into the skin to correct lines and wrinkles. Some people may experience the treatment as a mild discomfort. A local anaesthetic topical cream can be applied to the area prior to treatment for a more comfortable experience, by your Nubello-Restylane practitioner.
The lips are a highly sensitive part of the body and, therefore, additional anaesthesia may be required before lip enhancement. This is achieved most effectively by using a dental block or local anaesthetic.
Your Nubello-Restylane practitioner will be able to advise on suitable anaesthesia for your treatment.

What is the clinical experience behind Nubello-Restylane?

Nubello-Restylane was the first product of its type and is the world’s most tried and tested HA dermal filler available today. It is the benchmark for clinical excellence in its field. Its safety and effectiveness are clinically proven and supported by extensive clinical data with over 100 documented studies. Nubello-Restylane has been used since 1996 in more than 20 million treatments* worldwide. Galderma, the manufacturer of Nubello-Restylane, continually invests in research and development.

Are there different Nubello-Restylane products?

Nubello-Restylane consists of a range of different products designed to be used at different levels in the skin to meet your treatment needs and maximise your treatment results.

Nubello-Restylane fillers – Restore and enhance facial features
Nubello-Restylane / Nubello-Restylane Lidocaine
Nubello-Restylane Perlane / Nubello-Restylane Perlance Lidocaine
Nubello-Restylane Lip Volume
Nubello-Restylane SubQ / Nubello-Restylane SubQ Lidocaine

Nubello-Restylane Skinboosters – Revitalise and hydrate your skin
Nubello-Restylane Vital Light / Nubello-Restylane Vital Light Lidocaine
Nubello-Restylane Vital / Nubello-Restylane Vital Lidocaine

Discuss with your practitioner during your pre-treatment consultation what products best suits your needs.

Who is qualified to administer Nubello-Restylane treatments?

Only a medically qualified health professional should carry out a Nubello-Restylane treatment (Plastic Surgeons, Cosmetic Doctors, Dermatologists, Cosmetic Dentists, or Aesthetic Nurses). Your practitioner should have undertaken a Galderma recognised training course (ask to see their training certificate) for the treatment you are having and should have the appropriate insurance.

If in doubt, please contact Galderma (the manufacturers of Nubello-Restylane).

Who manufactures Nubello-Restylane?

Nubello-Restylane is produced by Galderma, a dermatology company that develops, manufactures and markets solutions for aesthetic and corrective treatments in more than 70 countries.
The division offers a complete worldwide portfolio in the aesthetic field including the brands Nubello-Restylane, Emervel, and Macrolane as well as other products improving patients’ health in the corrective field.
The site in Uppsala, Sweden, where Nubello-Restylane is produced is Galderma’s Global Center of Excellence for Aesthetic and Corrective solutions with state-of-the-art research, development and manufacturing facilities.
After over a decade of clinical use, over 20 million treatments* worldwide with continuous research and safety as top priority, Nubello-Restylane has been proven to be safe, effective and long-lasting. Galderma continues to invest in a research and development, in the interest of improving further patient safety and new product development.
Our UK office is based in Watford, Hertfordshire. For more information on Galderma visit www.galderma.co.uk.

Do I need to take a skin test?

No skin test is required as Nubello-Restylane does not contain any animal-derived ingredients.

Can Nubello-Restylane be used if I have had laser treatment or a chemical peel?

If you have recently had a laser or chemical peel treatment, it is recommended you wait until the area is totally healed and the skin is back to its normal condition. Consult your Nubello-Restylane practitioner for more information.

How is Nubello-Restylane produced?

Galderma has patented a unique technology, NASHA™, which stabilises hyaluronic acid to make it long lasting, yet similar to the body’s own hyaluronic acid. This means that a Nubello-Restylane treatment is safe and long lasting, minimising the risk of allergic reactions.

Nubello-Restylane Before & After Images

Whether you are looking to smooth away wrinkles, lines, folds or add volume to your facial features such as you cheeks, chin or lips, there is a Nubello-Restylane treatment suitable for your needs. In our before and after section, you will find a variety of images to see what Nubello-Restylane could do for you. Simply click on the area of interest and explore how Nubello-Restylane can help you release your best you. Want to find out more? Take a look at our treatments section or speak with your local Nubello-Restylane Practitioner today to find out how the Nubello-Restylane range of dermal fillers and Skinboosters can help you.

Mid Face- Cheeks|Nose


*Disclaimer: Plastic and cosmetic surgery is depends on person to person and their skin type, medical & health condition